SIGMA-2 RECEPTOR, METHOD OF SCREENING OF SPECIFIC LIGANDS AND USE OF THE SAME IN DIAGNOSTIC OR THERAPEUTIC METHODS

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Abstract

The present invention relates to the identification, isolation and characterization of the proteins forming the sigma-2 receptor. The invention further relates to the utilization of said proteins for preparing a screening for the sigma-2 receptor, as well as assay of specific candidate ligands to the use of the ligands for setting up diagnostic assays for tumour tissues and for preparing antitumour drugs. Lastly, the isolated proteins are utilized for producing anti-receptor antibodies, which likewise find employ in the diagnosis and therapeutic treatment of neoplasias.

Classe Tecnologica

A - Human Necessities

Patent Office

United States Patent and Trademark Office

Numero Deposito

US20090017038

Anno Deposito

2007

Anno Concessione

2009

Inventori Pugliesi

Tutti gli inventori

  • Colabufo Nicola Antonio
  • Berardi Francesco
  • Perrone Roberto

Titolari pugliesi

Tutti i titolari

  • Università Degli Studi Di Bari Aldo Moro
  • COLABUFO NICOLA ANTONIO
  • BERARDI FRANCESCO
  • PERRONE ROBERTO