Renal carcinoma cell line and uses thereof

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Abstract

The present invention relates to a renal carcinoma cell line capable of activating the immune system in an antigen-specific manner. According to a further aspect, the invention also includes derivatives of the cell line that maintain said activation capacity. The invention also comprises a method for targeting and activating immune system cells against cells of clear cell renal carcinoma. Said method comprises the co-incubation of isolated immune system cells (dendritic cells, CD4*, CD8* lymphocytes etc.) with cells of the RCC BA85#21 line in accordance with the invention in a suitable culture medium, for a time sufficient to obtain antigen specific cells.

Classe Tecnologica

A - Human Necessities

Patent Office

United States Patent and Trademark Office

Numero Deposito

US8128923

Anno Deposito

2005

Anno Concessione

2006

Inventori Pugliesi

Tutti gli inventori

  • Elena Ranieri
  • Michele Battaglia
  • Herr Wolfgang
  • Loreto Gesualdo

Titolari pugliesi

Tutti i titolari

  • Università Degli Studi Di Bari Aldo Moro
  • Università Degli Studi Di Foggia