Abstract

The aim of this paper was to propose a novel approach to the ultrasound (US) characterizationof human bones through an improved measurement of the apparent integratedbackscatter (AIB). Four intact human femoral heads were studied ex vivo in their physiologicmorphological configuration, including cartilaginous, cortical and trabecular regions.Each sample underwent an US acquisition performed with a clinically-available echographicdevice and a micro-computed tomography (micro-CT) scan, whose spatial resolutionwas preliminarily optimized for this specific purpose. A dedicated US signalcompensation was employed in the AIB computation, to take into account the variabilityof sample-probe distance and cortical bone thickness. Obtained results showed an appreciableglobal correlation between AIB and the trabecular bone volume fraction as quantifiedby the micro-CT parameter BV/TV (r = 0.69). The proposed approach has interestingperspectives for a clinical translation as an innovative method for in vivo US measurementof proximal femur bone density.

Autore Pugliese

• Conversano Francesco , Casciaro Sergio

Tutti gli autori

• T. De Marco; M. Peccarisi; F. Conversano; A. Greco;S. Chiozzi; F. De Pascalis ; S. Casciaro

Titolo volume/Rivista

Measurement

Anno di pubblicazione

2016

ISSN

0263-2241

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

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Numero di citazioni Scopus

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Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

Non Disponibile