Abstract

Enterococcus faecalis is a Gram-positive commensal inhabitant of the intestinal tract of humans, animals, and insects. However, it is also an opportunistic pathogen and has emerged as a leading cause of hospital-acquired extraintestinal infections. Fluoroquinolones have been frequently used to treat E. faecalis infections, and the emergence of fluoroquinolone-resistant E. faecalis strains has recently been reported in several countries. Thus, the identifications of new antibiotics specifically directed to E. faecalis may be envisaged. In this paper, a new series of N-1,3-benzothiazol-2-ylbenzamides have been designed, synthesized, and evaluated for their in vitro antimicrobial activities. Among the tested compounds, 3i was active against E. faecalis. © 2013 Domenico Armenise et al.

Autore Pugliese

• Carocci Alessia , Catalano Alessia , Rosato Antonio , Franchini Carlo , Corbo Filomena Faustina Rina

Tutti gli autori

• CAROCCI A.;CATALANO A.;ROSATO A.;FRANCHINI C.;CORBO F.F.R.;DE LAURENTIS N.

Titolo volume/Rivista

Non Disponibile

Anno di pubblicazione

2013

ISSN

2090-9063

ISBN

Non Disponibile

Numero di citazioni Wos

4

Ultimo Aggiornamento Citazioni

Non Disponibile

Numero di citazioni Scopus

7

Ultimo Aggiornamento Citazioni

Non Disponibile

Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile