Surface segregation assessment in poly(epsilon-Caprolactone)-poly(Ethylene Glycol) Multiblock Copolymer Films
Abstract
The ability to predict the in vivo performance of multiblock-copolymer-based biomaterials is crucial for their applicability in the biomedical field. In this work, XPS analysis of PCL-PEG copolymers was carried out, as well as morphological and wettability evaluations by SEM and CA measurements, respectively. XPS analysis on films equilibrated in PBS demonstrated a further enrichment in the PEG component on the surface. Copolymer films obtained by casting using different solvents showed a dependence in segregation according to the solvent employed. Cell adhesion tests demonstrated the importance of copolymer segregation and rearrangement in a wet environment, with a dependence of these phenomena on the copolymer molecular weight.
Autore Pugliese
Tutti gli autori
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DE GIGLIO E.;SABBATINI L.
Titolo volume/Rivista
Non Disponibile
Anno di pubblicazione
2010
ISSN
1616-5187
ISBN
Non Disponibile
Numero di citazioni Wos
Nessuna citazione
Ultimo Aggiornamento Citazioni
Non Disponibile
Numero di citazioni Scopus
16
Ultimo Aggiornamento Citazioni
Non Disponibile
Settori ERC
Non Disponibile
Codici ASJC
Non Disponibile
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