Surface segregation assessment in poly(epsilon-Caprolactone)-poly(Ethylene Glycol) Multiblock Copolymer Films

Abstract

The ability to predict the in vivo performance of multiblock-copolymer-based biomaterials is crucial for their applicability in the biomedical field. In this work, XPS analysis of PCL-PEG copolymers was carried out, as well as morphological and wettability evaluations by SEM and CA measurements, respectively. XPS analysis on films equilibrated in PBS demonstrated a further enrichment in the PEG component on the surface. Copolymer films obtained by casting using different solvents showed a dependence in segregation according to the solvent employed. Cell adhesion tests demonstrated the importance of copolymer segregation and rearrangement in a wet environment, with a dependence of these phenomena on the copolymer molecular weight.


Tutti gli autori

  • DE GIGLIO E.;SABBATINI L.

Titolo volume/Rivista

Non Disponibile


Anno di pubblicazione

2010

ISSN

1616-5187

ISBN

Non Disponibile


Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

Non Disponibile


Numero di citazioni Scopus

16

Ultimo Aggiornamento Citazioni

Non Disponibile


Settori ERC

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Codici ASJC

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