Simultaneous detection of multiple lower genital tract pathogens by an impedimetric immunochip

Abstract

Lower genital tract infections caused by both sexually and not-sexually transmitted pathogens in women are a key public health priority worldwide, especially in developing countries. Since standard analyses are time-consuming, appropriate therapeutic intervention is often neglected or delayed. Lab-on-chips and biosensors open new perspectives and offer innovative tools to simplify the diagnosis by medical staff, especially in countries with inadequate resources. Here we report a biosensing platform based on Electrochemical Impedance Spectroscopy (EIS) that allows multiplexed detection of Candida albicans, Streptococcus agalactiae and Chlamydia trachomatis with a single biochip, enabling a quick screening thanks to the presence of different immobilized antibodies, each specific for one of the different target pathogens.


Autore Pugliese

Tutti gli autori

  • Chiriacò M.S. , Primiceri E. , De Feo F. , Montanaro A. , Monteduro A.G. , Tinelli A. , Megha M. , Carati D. , Maruccio G.

Titolo volume/Rivista

BIOSENSORS & BIOELECTRONICS


Anno di pubblicazione

2016

ISSN

0956-5663

ISBN

Non Disponibile


Numero di citazioni Wos

4

Ultimo Aggiornamento Citazioni

28/04/2018


Numero di citazioni Scopus

4

Ultimo Aggiornamento Citazioni

28/04/2018


Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile