Preparation and characterization of Collagen/hydroxyapatite microsphere composite scaffold for bone regeneration
Abstract
In the present work Collagen/Hydroxyapatite microsphere (Col/mHA) scaffold with a multiscale porosity was prepared. Col/mHA composite scaffold was prepared by freezedrying/ dehydrothermal crosslinking method. The HA microspheres (mHA) were obtained by spray drying of nano hydroxyapatite slurry prepared by precipitation technique. XRD analysis revealed that the microspheres were composed only of pure HA phase and EDS analysis revealed that Ca/P ratio was 1.69. The obtained microsphere had an average diameter 6 microns, specific surface area of 40 m2/g by BET analysis and BJH analysis shows meso porous structure having an average pore diameter 16nm. SEM analysis shows that the obtained Col/mHA scaffold had a macro porosity ranging from micron to 200 microns with meso porous mHA embedded in the collagen matrix.
Autore Pugliese
Tutti gli autori
-
S. Kunjalukkal Padmanabhan , F. Gervaso , A. Sannino , A. Licciulli
Titolo volume/Rivista
Non Disponibile
Anno di pubblicazione
2014
ISSN
Non Disponibile
ISBN
Non Disponibile
Numero di citazioni Wos
2
Ultimo Aggiornamento Citazioni
27/04/2018
Numero di citazioni Scopus
2
Ultimo Aggiornamento Citazioni
26/04/2018
Settori ERC
Non Disponibile
Codici ASJC
Non Disponibile
Condividi questo sito sui social