METHOD OF SCREENING FOR THERAPEUTIC COMPOUNDS USEFUL IN DETOXIFYING CENTRAL NERVOUS SYSTEM FROM B-AMYLOID PEPTIDE

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Abstract

The present invention refers to a method and a kit of screening for therapeutic compounds useful in detoxifying central nervous system from ß-amyloid peptide. The method and kit involve the use of the beta amyloid peptide in the everted gut sac assay and allow assessing the inducing activity of the test compounds on the P-gp-mediated ß-amyloid peptide transport

Classe Tecnologica

G - Physics

Patent Office

World Intellectual Property Organization

Numero Deposito

WO2012159674

Anno Deposito

2011

Anno Concessione

2012

Inventori Pugliesi

Tutti gli inventori

  • Nicola Antonio Colabufo
  • Francesco Berardi
  • Carmela Inglese
  • Marcello Leopoldo
  • Maria Grazia Perrone
  • Roberto Perrone

Titolari pugliesi

Tutti i titolari

  • Università Degli Studi Di Bari Aldo Moro
  • Nicola Antonio Colabufo
  • Francesco Berardi
  • Carmela Inglese
  • Marcello Leopoldo
  • Maria Grazia Perrone
  • Roberto Perrone