Abstract

Aim of this paper was to assess the clinical effectiveness of a novel ultrasound (US) approach for the estimation of bone fragility. A total of 85 female patients (40-80. years) were recruited and underwent conventional DXA investigations of both lumbar spine and proximal femur, an abdominal US scan of the lumbar spine and the FRAX® questionnaire for the calculation of osteoporotic fracture probabilities. Acquired US data were analyzed through an automatic algorithm that calculated the Fragility Score (F.S.), a parameter that estimates skeletal fragility from dedicated spectral and statistical analyses. F.S. showed a good correlation with the most reliable fracture risk predictions obtained by FRAX® (r = 0.71, p <. 0.001). Since this correlation level with FRAX® outcomes was much better than lumbar BMD one (. r = 0.43) and very similar to that obtained for femoral neck BMD (. r = 0.72), F.S. has the potential to become a simple and non-ionizing method for bone fragility assessment.

Autore Pugliese

• Conversano Francesco , Casciaro Sergio

Tutti gli autori

• Greco A.; Pisani P.; Conversano F.; Soloperto G.; Renna M.D.; Muratore M.; Casciaro S.

Titolo volume/Rivista

Measurement

Anno di pubblicazione

2016

ISSN

0263-2241

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

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Numero di citazioni Scopus

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Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

Non Disponibile