Abstract

Organic field-effect transistors including a functional biorecognition interlayer, sandwiched between the dielectric and the organic semiconductor layers, have been recently proposed as ultrasensitive label-free biosensors capable to detect a target molecule in the low pM concentration range. The morphology and the structure of the stacked bilayer formed by the protein biointerlayer and the overlying organic semiconductor is here investigated for different protein deposition methods. X-ray scattering techniques and scanning electron microscopy allow us to gather key relevant information on the interface structure and to assess target analyte molecules capability to percolate through the semiconducting layer reaching the protein deposit lying underneath. Correlations between the structural and morphological data and the device analytical performances are established allowing us to gather relevant details on the sensing mechanism and further improving sensor performances, in particular in terms of sensitivity and selectivity. © 2014 American Chemical Society.

Autore Pugliese

• Giannini Cinzia , Altamura Davide , Di Franco Cinzia , Mallardi Antonia

Tutti gli autori

• Magliulo M.; Altamura D.; Di Franco C.; Santacroce M.V.; Manoli K.; Mallardi A.; Palazzo G.; Scamarcio G.; Giannini C.; Torsi L.

Titolo volume/Rivista

Journal of physical chemistry. C

Anno di pubblicazione

2014

ISSN

1932-7447

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

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Numero di citazioni Scopus

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Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

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