Abstract

The use of inorganic nanoparticles in biomedicine, in particular in the field of diagnosis andtherapy of human diseases, has rapidly grown in the last decades. Water solubilisation of thenanoparticles, especially for particles synthesized in non-polar solvents, is an essential prerequisitefor their biological exploitation. The encapsulation of surfactant coated nanoparticlesinto polymer shells represents one of the most suitable and most popular methods to make themwater soluble. Herein we provide an overview of the amphiphilic polymer molecules used andthe efforts undertaken to further tailor the surface of polymer coated nanoparticles withfluorescent dyes, chemical sensor molecules and small or large biomolecules for the preparationof bio-functional nanoprobes. Their biological implications, highlighting limitations andchallenges, are also discussed.

Autore Pugliese

• Quarta Alessandra

Tutti gli autori

• Quarta A. ; Curcio A. ; Kakwere H. ; Pellegrino T.

Titolo volume/Rivista

Nanoscale

Anno di pubblicazione

2012

ISSN

2040-3372

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

Non Disponibile

Numero di citazioni Scopus

Non Disponibile

Ultimo Aggiornamento Citazioni

Non Disponibile

Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile