Abstract

The improvement of scaffold performances as cell carriers in a tissue implant is still a challenge in tissue engineering. Since cells in contact with a scaffold firstly sense its top surface before interacting with its macro-/micro-porous structure, the insertion of chemical motifs within the body of the scaffold could improve cell colonization through its entire structure. In this study, combinations of plasma deposition and treatment processes have been employed to create chemical gradients inside polycaprolactone porous scaffolds, whose micro-morphology has been finely characterized with synchrotron radiation computed micro-tomography. The graded chemical composition of these scaffolds has successfully allowed the increase of cell viability with respect to untreated materials.

Autore Pugliese

• Sardella Eloisa

Tutti gli autori

• Intranuovo F.; Gristina R.; Brun F.; Mohammadi S.; Ceccone G.; Sardella E.; Rossi F.; Tromba G.; Favia P.

Titolo volume/Rivista

Plasma processes and polymers

Anno di pubblicazione

2014

ISSN

1612-8850

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

Non Disponibile

Numero di citazioni Scopus

Non Disponibile

Ultimo Aggiornamento Citazioni

Non Disponibile

Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile