Abstract

IntroductionOne of the most pressing need of modern research is efficient data sharing and integration, but tools and legislation about standards and Standard Operating Procedures (SOPs) that scientists can currently use are still not enough comprehensive, efficient and well harmonised.The production of omics data, by the use of High Throughput Next Generation Sequencing Technologies (HT-NGS), is providing incredible amounts of data at a rate much higher than the one taken to the scientists for to analyse and interpret them. This unbalanced situation prevents the scientific community to exploit the full potential that this "data production revolution" provides.The use of standards for the production and publication of research data is essential to maximize the results of research efforts and technology transfer because only standards can assure and ensure quality, efficient sharing and data interoperability. Reproducibility is essential for good research practices and reproducibility of data and experimental procedures can be obtained only if research data are produced and published by adhering to well established quality standards. Standards and SOPs must be key elements of any research project and be adopted in lab procedure as well as for in silico data production, storage and analysis.The CHARME project: "Harmonising standardisation strategies to increase efficiency and competitiveness of European life-science research", is a COST Action (CA 15110) whose main goal is to unite experts from all areas of scientific research and strategic development (academia, industry, policy, legal, ethical, etc.), joining their expertise to address needs and challenges along the value chain for life sciences research across Europe. The objectives are to address main gaps in standards and SOPs in different research domains, co-ordinate current research efforts in this field, integrate different stakeholder groups in CHARME's activities, co-develop a common research roadmap on quality management and standardization to provide the European Commission the support for the positioning of Europe as a "leading partner" in international standardisation and standardisation activities in life sciences, including input for technology transfer and cooperation with private enterprises.MethodsTo achieve the CHARME's 4-year vision, an integrated project strategy has been designed to ensure de-centralised decision-making and enhanced cooperation between the different stakeholders and partners. The leverage of the COST Action CHARME relates to four pillars: 1) the creation of a network of all relevant stakeholder groups involved in standardisation, to exchange and harmonise activities; 2) the development of a cross-cutting education and training strategy to raise awareness and facilitate the implementation of standards and SOPs; 3) strengthening of innovation creation and technology transfer; 4) strategy development to urge the implementation of standards and SOPs. This

Autore Pugliese

• D'elia Domenica

Tutti gli autori

• D. D'Elia; B. Regierer; T.K. Attwood; E. Bongcam-Rudloff; S. Holmann

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Anno di pubblicazione

2016

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