Abstract

The aim of this study is to assess the accuracy of a novel ultrasound (US) approach for lumbar spine densitometry on overweight and obese women of variable age through a clinical validation study. The US method was originally developed in women with body mass index (BMI) < 25 kg/m2. In this study, 382 female patients were recruited (45-80 years, BMI > 25 kg/m2) and underwent dual X-ray absorptiometry (DXA) of lumbar spine (L1-L4) and an US scan of the same vertebrae L1-L4, performed with a dedicated device providing both echographic images and 'raw' radiofrequency signals. Acquired US data were analysed through a novel automatic algorithm that performed a series of spectral and statistical analyses to calculate bone mineral density employing an innovative method. Diagnostic accuracy of US investigations was quantitatively assessed through a direct comparison with DXA results. The average agreement between US and DXA diagnoses was acceptable for patients aged 45-65 years (81.5%), while a slight decrement was observed for older patients (69.6%), which can be partially due to a decrease in DXA accuracy because of age-related degenerations. The adopted method has a potential for early osteoporosis diagnosis in people younger than 65 years, independent of their BMI.

Autore Pugliese

• Casciaro Ernesto , Conversano Francesco , Casciaro Sergio

Tutti gli autori

• Casciaro S.; Pisani P.; Conversano F.; Renna M.D.; Soloperto G.; Casciaro E.; Quarta E.; Grimaldi A.; Muratore M.

Titolo volume/Rivista

IET science, measurement & technology

Anno di pubblicazione

2016

ISSN

1751-8822

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

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Numero di citazioni Scopus

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Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

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