Hepatopancreas mitochondria of Mytilus galloprovincialis: effect of zinc ions on mitochondrial bioenergetics and metabolism

Abstract

Oxygen uptake, respiratory complexes, and metabolic activities have been studied in mitochondria isolated from thehepatopancreata of Mytilus galloprovincialis collected in the "Mar Grande" of Taranto (Ionian Sea, Italy). Although exposure to 5.0 ?gZn2+/L resulted in a significant increase of states 3 and 4 respiration with glutamate + pyruvate as respiratory substrate, it was foundthat the exposure of mussels to different concentrations of Zn2+ (2.5-7.5 ?g/L) neither inhibited mitochondrial respiration nor exertedany inhibitory effect on representative mitochondrial dehydrogenases. It rather stimulates these activities, producing an extra synthesisof adenosine triphosphate by hepatopancreas mitochondria and possibly increasing its availability in the cytoplasmic compartment.This might be considered as a specific strategy utilized by the mussel to cope with variations in the heavy metals content of the marineenvironment, and it could be used to detect toxic effects.


Tutti gli autori

  • A. DE LISI; E. PRATO; F. BIANDOLINO; G. SARLI;D. NEGRO; G. LA PIANA; D. MARZULLI

Titolo volume/Rivista

Turkish journal of biology


Anno di pubblicazione

2013

ISSN

1300-0152

ISBN

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Nessuna citazione

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