Hepatopancreas mitochondria of Mytilus galloprovincialis: effect of zinc ions on mitochondrial bioenergetics and metabolism
Abstract
Oxygen uptake, respiratory complexes, and metabolic activities have been studied in mitochondria isolated from thehepatopancreata of Mytilus galloprovincialis collected in the "Mar Grande" of Taranto (Ionian Sea, Italy). Although exposure to 5.0 ?gZn2+/L resulted in a significant increase of states 3 and 4 respiration with glutamate + pyruvate as respiratory substrate, it was foundthat the exposure of mussels to different concentrations of Zn2+ (2.5-7.5 ?g/L) neither inhibited mitochondrial respiration nor exertedany inhibitory effect on representative mitochondrial dehydrogenases. It rather stimulates these activities, producing an extra synthesisof adenosine triphosphate by hepatopancreas mitochondria and possibly increasing its availability in the cytoplasmic compartment.This might be considered as a specific strategy utilized by the mussel to cope with variations in the heavy metals content of the marineenvironment, and it could be used to detect toxic effects.
Autore Pugliese
Tutti gli autori
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A. DE LISI; E. PRATO; F. BIANDOLINO; G. SARLI;D. NEGRO; G. LA PIANA; D. MARZULLI
Titolo volume/Rivista
Turkish journal of biology
Anno di pubblicazione
2013
ISSN
1300-0152
ISBN
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