Abstract

The efficacy of four agricultural byproducts (ABPs) and two commercial binders (CBs) to reduce the gastrointestinal absorption of a mixture of mycotoxins was tested in piglets using urinary mycotoxin biomarkers as indicator of the absorbed mycotoxins. Twenty-eight piglets were administered a bolus contaminated with the mycotoxin mixture containing or not ABP or CB. Twenty-four hour urine was collected and analyzed for mycotoxin biomarkers by using a multiantibody immunoaffinity-based LC-MS/MS method. Each bolus contained 769 ?g of fumonisin B1 (FB1), 275 ?g of deoxynivalenol (DON), 29 ?g of zearalenone (ZEN), 6.5 ?g of aflatoxin B1 (AFB1) and 6.6 ?g of ochratoxin A (OTA) corresponding to 2.2,0.8, 0.08, 0.02, and 0.02 ?g/g in the daily diet, respectively. The percentage of ABP in each bolus was 50%, whereas for the two CBs the percentages were 5.2 and 17%, corresponding to 2.8, 0.3, and 0.9% in the daily diet, respectively. The reduction of mycotoxin absorption was up to 69 and 54% for ABPs and CBs, respectively. White grape pomace of Malvasia was the most effective material as it reduced significantly (p < 0.05) urinary mycotoxin biomarker of AFB1 (67%) and ZEN (69%), whereas reductions statistically not significant were observed for FB1 (57%), DON (40%), and OTA (27%). This study demonstrates that grape pomace reduces the gastrointestinal absorption of mycotoxins. This agricultural byproduct can be considered an alternative to commercial products and used in the feed industries as an effective, cheap, and natural binder for multiple mycotoxins.

Autore Pugliese

• Avantaggiato Giuseppina , Gambacorta Lucia , Solfrizzo Michele

Tutti gli autori

• L. Gambacorta; P. Pinton; G. Avantaggiato; I.P. Oswald; M. Solfrizzo

Titolo volume/Rivista

Journal of agricultural and food chemistry

Anno di pubblicazione

2016

ISSN

1520-5118

ISBN

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Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

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Numero di citazioni Scopus

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Settori ERC

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Codici ASJC

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