Abstract

The role of plant tyrosyl-DNA phosphodiesterase 1? in genome stability is studied using a Medicago truncatula MtTdp1?-depleted line. Lack of MtTdp1? results in a 39% reduction of methylated cytosines as compared to control. RNA-Seq analyses revealed that 11 DNA transposons and 22 retrotransposons were differentially expressed in the Tdp1?-2a line. And among them all DNA transposons (MuDR, hAT, DNA3-11_Mad) and seven retrotransposons (LTR/Gipsy, LTR/Copia, LTR and NonLTR/L1) were down-regulated, while remaining 15 retrotransposons were up-regulated. Results suggest that the occurrence of stress-responsive cis-elements as well as changes in the methylation pattern at the LTR promoters might be responsible for the enhanced retrotransposon transcription.

Autore Pugliese

• Leonetti Paola

Tutti gli autori

• Sabatini M.E.; Donà M.; Leonetti P.; Minio A.; Delledonne M.; Carbonera D.; Confalonieri M.; Giraffa G.; Balestrazzi A.

Titolo volume/Rivista

Journal of integrative plant biology

Anno di pubblicazione

2016

ISSN

1744-7909

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

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Numero di citazioni Scopus

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Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

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