Abstract

In this article a nonnegative blind source separation technique, known as nonnegative matrix factorization, is applied to microdiffraction data in order to extract characteristic patterns and to determine their spatial distribution in tissue typing problems occurring in bone-tissue engineering. In contrast to other blind source separation methods, nonnegative matrix factorization only requires nonnegative constraints on the extracted sources and corresponding weights, which makes it suitable for the analysis of data occurring in a variety of applications. In particular, here nonnegative matrix factorization is hierarchically applied to two-dimensional meshes of X-ray diffraction data measured in bone samples with implanted tissue. Such data are characterized by nonnegative profiles and their analysis provides significant information about the structure of possibly new deposited bone tissue. A simulation and real data studies show that the proposed method is able to retrieve the patterns of interest and to provide a reliable and accurate segmentation of the given X-ray diffraction data.

Autore Pugliese

• Ladisa Massimo , Lamura Antonio , Laudadio Teresa

Tutti gli autori

• M. Ladisa; A. Lamura; T. Laudadio

Titolo volume/Rivista

Journal of applied crystallography

Anno di pubblicazione

2013

ISSN

0021-8898

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

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Numero di citazioni Scopus

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Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

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