Biodegradability of pharmaceutical industrial wastewater and formation of recalcitrant organic compounds during aerobic biological treatment

Abstract

The biodegradability of different wastewater samples originated from the industrial production of threepharmaceuticals (naproxen, acyclovir, and nalidixic acid) was performed through the standard Zahn-Wellens test. Moreover, the wastewater composition before and during the test was evaluated in termsof parent compounds and main metabolites by LC/MS, and the biodegradability of the parent compoundswas also assessed by performing extra Zahn-Wellens tests on synthetic solutions. The results, besidesshowing the relatively good biodegradability of acyclovir and naproxen, evidenced the masking role ofthe organic matrices, especially in the case of nalidixic acid. The latter compound showed to berecalcitrant and persistent, despite the apparently good performance of the Zahn-Wellens test. Deeperevaluation evidenced that the biodegradation of high concentrations of organic solvents and other biodegradablecompound tended to ''hide" the lack of removal of the target compound.


Tutti gli autori

  • MASCOLO G.; BALEST L.; CASSANO D.; LAERA G.; LOPEZ A.; POLLICE A.; SALERNO C.

Titolo volume/Rivista

Bioresource technology


Anno di pubblicazione

2010

ISSN

0960-8524

ISBN

Non Disponibile


Numero di citazioni Wos

Nessuna citazione

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Numero di citazioni Scopus

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Settori ERC

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Codici ASJC

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