Abstract

The microbial contamination in food packaging has been a major concern that paved the way to search for novel, natural anti-microbial agents, such as modified ?-mangostin. In the present study, twelve synthetic analogs were obtained through semi-synthetic modification of ?-mangostin by Ritter reaction, reduction by palladium-carbon (Pd-C), alkylation, and acetylation. The evaluation of the anti-microbial potential of the synthetic analogs showed higher bactericidal activity than the parent molecule. The anti-microbial studies proved that I E showed high anti-bacterial activity whereas I I showed the highest anti-fungal activity. Due to their microbicidal potential, modified ?-mangostin derivatives could be utilized as active anti-microbial agents in materials for the biomedical and food industry.

Autore Pugliese

• Poltronieri Palmiro

Tutti gli autori

• S. Narasimhan; S. Maheshwaran; I.A. Abu-Yousef; A.F. Majdalawieh; J. Rethavathi; P.Edwin Das; P. Poltronieri

Titolo volume/Rivista

Molecules

Anno di pubblicazione

2017

ISSN

1420-3049

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

Non Disponibile

Numero di citazioni Scopus

Non Disponibile

Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

Non Disponibile