Abstract

The aim of this paper was to investigate the clinical feasibility and the accuracy in femoral neck densitometryof the Osteoporosis Score (O.S.), an ultrasound (US) parameter for osteoporosis diagnosis that has beenrecently introduced for lumbar spine applications. A total of 377 female patients (aged 61-70 y) underwent both afemoral dual X-ray absorptiometry (DXA) and an echographic scan of the proximal femur. Recruited patientswere sub-divided into a reference database used for ultrasound spectral model construction and a study populationfor repeatability assessments and accuracy evaluations. Echographic images and radiofrequency signals wereanalyzed through a fully automatic algorithm that performed a series of combined spectral and statistical analyses,providing as a final output the O.S. value of the femoral neck. Assuming DXA as a gold standard reference, theaccuracy of O.S.-based diagnoses resulted 94.7%, with k 5 0.898 (p , 0.0001). Significant correlations werealso found between O.S.-estimated bone mineral density and corresponding DXA values, with r2 up to 0.79 androot mean square error 5 5.9-7.4%. The reported accuracy levels, combined with the proven ease of use andvery good measurement repeatability, provide the adopted method with a potential for clinical routine applicationin osteoporosis diagnosis. (

Autore Pugliese

• Conversano Francesco , Casciaro Sergio

Tutti gli autori

• Casciaro S.; Peccarisi M.; Pisani P.; Franchini R.; Greco A.; De Marco T.; Grimaldi A; Quarta L.; Quarta E.; Muratore M.; Conversano F.

Titolo volume/Rivista

Ultrasound in medicine & biology

Anno di pubblicazione

2016

ISSN

0301-5629

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

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Numero di citazioni Scopus

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Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

Non Disponibile