Allergenic and novel food proteins: state of the art and challenges in the allergenicity assessment

Abstract

There is an increasing demand for animal-derived products in the developing countries. This posesmajor concerns for the sustainable production of safe and nutritious food. Consequently, to address these needsalternative sustainable sources of valuable dietary proteins are sought for.Scope and approach: In this review, we discuss alternative protein sources for human food consumption such asnovel foods derived from other animal sources like insects. Before these novel foods can enter the market place,their safety for consumers should be demonstrated. We herein provide an overview of the legislative frameworkcurrently in place across Europe, the key elements required for allergenicity assessment of novel foods, the toolsat disposal for allergenicity prediction and the most advanced technologies available for food allergen detectionand characterization.Key finding and conclusions: Effective characterization of potential protein-based allergenic hazards in novel foodingredients is essential to support effective risk assessment. Development of a cost-effective, validated tool box toallow improved hazard characterization for allergenicity risk assessment is needed. Although novel methodologies, such as mass spectrometry, have great potential for allergen characterization and allergen detection indifferent food contributing to reduce the risk for allergic consumers, some work is still required for methodvalidation and the creation of protein sequence databases for proteomic analysis.


Autore Pugliese

Tutti gli autori

  • Pali-Scholl I.; Veroexckx K.; Mafra I.; Bavaro S.L.; Mills E.N.C.; Monaci L.

Titolo volume/Rivista

Trends in food science & technology


Anno di pubblicazione

2018

ISSN

0924-2244

ISBN

Non Disponibile


Numero di citazioni Wos

Nessuna citazione

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Numero di citazioni Scopus

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Settori ERC

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Codici ASJC

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