Abstract

Smart materials able to sense environmental stimuli can be exploited as intelligent carrier systems. Acidic pHresponsive polymers, for instance, exhibit a variation in the ionization state upon lowering the pH, which leads to their swelling. The different permeability of these polymers as a function of the pH could be exploited for the incorporation and subsequent release of previously trapped payload molecules/nanoparticles. We provide here a proof of concept of a novel use of pH-responsive polymer nanostructures based on 2-vinylpyridine and divinylbenzene, having an overall size below 200 nm, as cargo system for magnetic nanoparticles, for oligonucleotide sequences, as well as for their simultaneous loading and controlled release mediated by the pH. © 2010 American Chemical Society.

Autore Pugliese

• Quarta Alessandra

Tutti gli autori

• Deka S.R.; Quarta A.; Di Corato R.; Falqui A.; Manna L.; Cingolani R.; Pellegrino T.

Titolo volume/Rivista

Langmuir

Anno di pubblicazione

2010

ISSN

1520-5827

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

Non Disponibile

Numero di citazioni Scopus

Non Disponibile

Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

Non Disponibile