Abstract

In an explorative study of the opportunities for synthesis provided by oxidation of natural aminoacidic compound with methyl-(trifluoromethyl)dioxirane, we noticed that oxidation of the cyclic compound, when successful, leads to the ?-hydroxy compound, notwithstanding the presence of the isopropyl groups that are usually easy targets for this reaction, as verified with the homologous acyclic compound. We therefore initiated an ab-initio study of the reactions aimed at determining the role of the ring and explaining the reactivity differences of the cis and trans configurations. Consistently with recent literature, we confirm the fundamental role of an adduct configuration in which the dioxirane O-O bond is largely divaricated and electron pairing is broken, often denoted in the literature as diradicaloid.

Autore Pugliese

• Fusco Caterina

Tutti gli autori

• Annese C.; D'Accolti L.; Fusco C.; Ciriaco F.

Titolo volume/Rivista

Communications in computer and information science

Anno di pubblicazione

2016

ISSN

1865-0929

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

Non Disponibile

Numero di citazioni Scopus

Non Disponibile

Ultimo Aggiornamento Citazioni

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Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile