Abstract

Aim of this paper was to assess the discrimination power of a novel ultrasound (US) parameter, called theFragility Score (F.S.), in the early identification of subjects prone to osteoporotic fractures. A total of 102female patients were recruited: 49 with a recent osteoporotic fracture (''frail" subjects), 53 were controlswithout fracture history (''non-frail" subjects). All the patients underwent a spinal DXA (dual X-rayabsorptiometry) and an abdominal US scan of lumbar vertebrae. Acquired US data were analyzed by anovel algorithm, which calculated the F.S. through spectral and statistical analyses involving both echographicimages and corresponding ''raw" signals. F.S. showed a good performance in discriminating ''frail"from ''non-frail" subjects (sensitivity = 76%, specificity = 68%), resulting even slightly more effective thanDXA-measured BMD (sensitivity = 73%, specificity = 66%). This methodology has a potential to become aneffective tool for the early identification, and timely treatment, of ''frail" subjects.

Autore Pugliese

• Conversano Francesco , Casciaro Sergio

Tutti gli autori

• P. Pisani; A. Greco; F. Conversano; M.D. Renna; E. Casciaro; L. Quarta; D. Costanza; M. Muratore; S. Casciaro

Titolo volume/Rivista

Measurement

Anno di pubblicazione

2016

ISSN

0263-2241

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

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Numero di citazioni Scopus

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Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

Non Disponibile