Abstract

We investigated the possible clinical feasibility and accuracy of an innovative ultrasound (US) method for diagnosis of osteoporosis of the spine. A total of 342 female patients (aged 51-60 y) underwent spinal dual X-ray absorptiometry and abdominal echographic scanning of the lumbar spine. Recruited patients were subdivided into a reference database used for US spectral model construction and a study population for repeatability and accuracy evaluation. US images and radiofrequency signals were analyzed via a new fully automatic algorithm that performed a series of spectral and statistical analyses, providing a novel diagnostic parameter called the osteoporosis score (O.S.). If dual X-ray absorptiometry is assumed to be the gold standard reference, the accuracy of O.S.-based diagnoses was 91.1%, with k = 0.859 (p < 0.0001). Significant correlations were also found between O.S.-estimated bone mineral densities and corresponding dual X-ray absorptiometry values, with r(2) values up to 0.73 and a root mean square error of 6.3%-9.3%. The results obtained suggest that the proposed method has the potential for future routine application in US-based diagnosis of osteoporosis. (C) 2015 World Federation for Ultrasound in Medicine & Biology.

Autore Pugliese

• Casciaro Ernesto , Conversano Francesco , Di Paola Marco , Franchini Roberto , Casciaro Sergio

Tutti gli autori

• Conversano F.; Franchini R.; Greco A.; Soloperto G.; Chiriacò F.; Casciaro E.; Aventaggiato M.; Renna M.D.; Pisani P.; Di Paola M.; Grimaldi A.; Quarta L.; Quarta E.; Muratore M.; Laugier P.; Casciaro S.

Titolo volume/Rivista

Ultrasound in medicine & biology

Anno di pubblicazione

2015

ISSN

0301-5629

ISBN

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Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

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Numero di citazioni Scopus

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Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

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