Abstract

Aim: to assess the overall diagnostic accuracy of whole-body MR-DWIBS compared to 18FDG-PET/CT, considered the reference standard of whole body tumour imaging modalities, in a series of consecutive patients with malignant tumour. Methods: 14 patients diagnosed with a malignant tumour over a four-month period were enrolled in this retrospective, observational study. The PET/CT and MR-DWIBS images were reviewed, in double blind, by a nuclear medicine physician and radiologists with 4 years experience. Lesion size, SUV and ADC were measured and calculated for each lesion. Results: The qualitative analysis of MR-DWIBS and 18FDG-PET/CT showed that one patient was negative at both techniques. MR-DWIBS was positive in 13 patients, 9 of whom were positive and 4 negative at 18FDG-PET/CT, respectively. 94 lesions were identified by MR-DWIBS and 68 by 18FDG-PET/CT, a significative discordance was found. The correlation between SUV and ADC of the lesions positive at both techniques was not statistically significant. The mean difference between the lesion size in 18FDG-PET/CT and MR-DWIBS was not statistically significant. No correlation was found between glucose metabolism and water motion. Conclusions: The results of this observational, retrospective study show that MR-DWIBS may be used to evaluate localization of parenchymal neoplasms but is less efficacious in characterizing lymphnode and skeletal lesions. 18FDG-PET/CT remains the best whole-body technique to identify lymphnode and skeletal lesions. 18FDG-PET/CT limit is identifying tumours with low glucose metabolism as in mucinous neoplasms. MR-DWIBS evaluation must be integrated with morphological images in order to increase the diagnostic accuracy of MR.

Autore Pugliese

• Niccoli Asabella Artor , Rubini Giuseppe

Tutti gli autori

• NICCOLI ASABELLA A.;RUBINI G.

Titolo volume/Rivista

Non Disponibile

Anno di pubblicazione

2012

ISSN

0033-8362

ISBN

Non Disponibile

Numero di citazioni Wos

16

Ultimo Aggiornamento Citazioni

Non Disponibile

Numero di citazioni Scopus

29

Ultimo Aggiornamento Citazioni

Non Disponibile

Settori ERC

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Codici ASJC

Non Disponibile