Restoration of host–microbiota homeostasis for attaining healthy aging: the role of milk and fermented milk

Abstract

Intestinal microbiota and gut-associated lymphoreticular tissue are in a dynamic equilibrium, the rupture of which causes a condition of dysbiosis in the host. Among many natural foods, milk, because of its composition, is able to influence the host–microbiota relationship. Donkey’s and goat’s milk represents a good alternative to human milk. Healthy effects of both kinds of milk have been reported in either in vitro or in vivo experiments. When administered to elderly subjects, donkey’s milk increased the release of interleukins 6 and 8, while goat’s milk exerted opposite effects. With special reference to fermented cow’s milk, a symbiotic (Gorbach and Goldin) when administered to another group of elderly people, behaved as donkey’s milk upregulating interleukins 6, 8 and also 1. In conclusion, the ability of milk and fermented milk to modulate the altered immune response in senescence needs to be exploited more for maintaining healthy aging.


Autore Pugliese

Tutti gli autori

  • JIRILLO E.;JIRILLO F.;MAGRONE T.

Titolo volume/Rivista

Non Disponibile


Anno di pubblicazione

2011

ISSN

1973-7998

ISBN

Non Disponibile


Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

Non Disponibile


Numero di citazioni Scopus

3

Ultimo Aggiornamento Citazioni

Non Disponibile


Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile