Microvesicles in the brain: Biomarker, messenger or mediator?
Abstract
Microvesicles (MVs) are cell-derived vesicles produced after membrane remodeling of eukaryotic cells during activation or apoptosis. MVs are considered a novel biomarker/messenger for many diseases. Neurons, astrocytes, microglia, as well as neural stem cells, have been described to release MVs, many studies have demonstrated the involvement of platelets and endothelial MVs in some central nervous diseases. This review is focused on understanding the role of MVs in the brain; new findings demonstrated that MVs can contribute to the onset and progression of some neurodegenerative and neuroinflammatory diseases, as well as to the development and regeneration of the nervous system.
Autore Pugliese
Tutti gli autori
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PANARO M.A.
Titolo volume/Rivista
Non Disponibile
Anno di pubblicazione
2015
ISSN
0165-5728
ISBN
Non Disponibile
Numero di citazioni Wos
21
Ultimo Aggiornamento Citazioni
Non Disponibile
Numero di citazioni Scopus
19
Ultimo Aggiornamento Citazioni
Non Disponibile
Settori ERC
Non Disponibile
Codici ASJC
Non Disponibile
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