Microvesicles in the brain: Biomarker, messenger or mediator?

Abstract

Microvesicles (MVs) are cell-derived vesicles produced after membrane remodeling of eukaryotic cells during activation or apoptosis. MVs are considered a novel biomarker/messenger for many diseases. Neurons, astrocytes, microglia, as well as neural stem cells, have been described to release MVs, many studies have demonstrated the involvement of platelets and endothelial MVs in some central nervous diseases. This review is focused on understanding the role of MVs in the brain; new findings demonstrated that MVs can contribute to the onset and progression of some neurodegenerative and neuroinflammatory diseases, as well as to the development and regeneration of the nervous system.


Tutti gli autori

  • PANARO M.A.

Titolo volume/Rivista

Non Disponibile


Anno di pubblicazione

2015

ISSN

0165-5728

ISBN

Non Disponibile


Numero di citazioni Wos

21

Ultimo Aggiornamento Citazioni

Non Disponibile


Numero di citazioni Scopus

19

Ultimo Aggiornamento Citazioni

Non Disponibile


Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile