Depression of cellular immunity correlated to stress: questions on welfare and protection in italian trotters after running performance
Abstract
In all Equestrian sports, the welfare of the horse must be paramount and must never be subordinated to competitive or commercial influences. It is necessary to prohibit any training methods which are abusive or cause fear or for which the horse has not been properly trained. The purpose of this study was to examine the effects of prolonged and intensive physical training on the immune response in trotter horses in order to recommend at the legislator the adoption of guidelines for the welfare of these animals. In fact, during their athletic life and some of them undergo lethal lung infections, therefore it is likely that modifications of physiologic cellular parameters could account for the increased susceptibility to microbial disease. Noteworthy, chronic stress has been shown to be immunosuppressive, whereas acute stress seems to lead to immunoenhancing effects. In particular, we have studied some immune parameters as blood cells distribution, hemoglobin, hematocrit, erythrocyte sedimentation rate, phagocytosis activity, macrophage Migration Inhibiting Factor (MIF) and finally the levels of (1-3)-ß-D-Glucan, as indicator of clearance. Taken together, these findings indicate a condition of reduced immune response in seven trotters after race, to identify possible biomarkers of stress dependent on physical exercise.
Autore Pugliese
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PASSANTINO L.
Titolo volume/Rivista
Non Disponibile
Anno di pubblicazione
2010
ISSN
0970-938X
ISBN
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Nessuna citazione
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Settori ERC
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Codici ASJC
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