Clinical and molecular observations on two fatal cases of rotavirus-associated enteritis in Italian children

Abstract

Two fatal cases of infantile rotavirus enteritis occurred in northern Italy in 2005. Both children were severely dehydrated, and death was related to severe cerebral edema. Histological examination demonstrated extensive damage of the intestinal epithelium, villous atrophy or blunting, and macrophage infiltration. The two rotavirus strains were of the G1P[8] type and the long electropherotype. The 2005 G1P[8] rotaviruses differed in the NSP4, VP3, VP4, and VP7 genes from G1P[8] rotaviruses circulating in 2004, suggesting the onset of a new G1P[8] strain in the local population.


Autore Pugliese

Tutti gli autori

  • MARTELLA V.

Titolo volume/Rivista

Non Disponibile


Anno di pubblicazione

2011

ISSN

0095-1137

ISBN

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Numero di citazioni Wos

7

Ultimo Aggiornamento Citazioni

Non Disponibile


Numero di citazioni Scopus

8

Ultimo Aggiornamento Citazioni

Non Disponibile


Settori ERC

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Codici ASJC

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