BioMaS: a modular pipeline for Bioinformatic analysis of Metagenomic AmpliconS

Abstract

Substantial advances in microbiology, molecular evolution and biodiversity have been carried out in recent years thanks to Metagenomics, which allows to unveil the composition and functions of mixed microbial communities in any environmental niche. If the investigation is aimed only at the microbiome taxonomic structure, a target-based metagenomic approach, here also referred as Meta-barcoding, is generally applied. This approach commonly involves the selective amplification of a species-specific genetic marker (DNA meta-barcode) in the whole taxonomic range of interest and the exploration of its taxon-related variants through High-Throughput Sequencing (HTS) technologies. The accessibility to proper computational systems for the large-scale bioinformatic analysis of HTS data represents, currently, one of the major challenges in advanced Meta-barcoding projects.


Autore Pugliese

Tutti gli autori

  • PESOLE G.

Titolo volume/Rivista

Non Disponibile


Anno di pubblicazione

2015

ISSN

1471-2105

ISBN

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Numero di citazioni Wos

16

Ultimo Aggiornamento Citazioni

Non Disponibile


Numero di citazioni Scopus

16

Ultimo Aggiornamento Citazioni

Non Disponibile


Settori ERC

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Codici ASJC

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