Aorta structural alterations in term neonates: the role of birth and maternal characteristics.
Abstract
AIM: To evaluate the influence of selected maternal and neonatal characteristics on aorta walls in term, appropriately grown-for-gestational age newborns. METHODS: Age, parity, previous abortions, weight, height, body mass index before and after delivery, smoking, and history of hypertension, of diabetes, of cardiovascular diseases, and of dyslipidemia were all assessed in seventy mothers. They delivered 34 males and 36 females healthy term newborns who underwent ultrasound evaluation of the anteroposterior infrarenal abdominal aorta diameter (APAO), biochemical profile (glucose, insulin, total cholesterol, HDL and LDL cholesterol, triglycerides, fibrinogen, and D-dimers homeostasis model assessment [HOMAIR]index), and biometric parameters. RESULTS: APAO was related to newborn length (r = +0.36; P = 0.001), head circumference (r = +0.37; P = 0.001), gestational age (r = +0.40, P = 0.0005), HOMA index (r = +0.24; P = 0.04), and D-dimers (r = +0.33, P = 0.004). Smoke influenced APAO values (odds ratio: 1.80; confidence interval 95%: 1.05-3.30), as well as diabetes during pregnancy (r = +0.42, P = 0.0002). Maternal height influenced neonatal APAO (r = +0.47, P = 0.00003). Multiple regression analysis outlined neonatal D-dimers as still significantly related to neonatal APAO values. CONCLUSIONS: Many maternal and neonatal characteristics could influence aorta structures. Neonatal D-dimers are independently related to APAO.
Autore Pugliese
Tutti gli autori
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ZITO A.;DI MAURO A.;FORNARELLI F.;SCHETTINI F.;CORTESE F.;CICCONE M.M.;GESUALDO M.;LAFORGIA N.;SCICCHITANO P.
Titolo volume/Rivista
Non Disponibile
Anno di pubblicazione
2013
ISSN
2314-6141
ISBN
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Numero di citazioni Wos
10
Ultimo Aggiornamento Citazioni
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Numero di citazioni Scopus
9
Ultimo Aggiornamento Citazioni
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Settori ERC
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Codici ASJC
Non Disponibile
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