Additive Role of a Potentially Reversible Cognitive Frailty Model and Inflammatory State on the Risk of Disability: The Italian Longitudinal Study on Aging

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Abstract

Cognitive frailty is a condition recently defined by operationalized criteria describing the simultaneous presence of physical frailty and mild cognitive impairment (MCI). Two subtypes for this clinical construct have been proposed: "potentially reversible" cognitive frailty (physical frailty plus MCI) and "reversible" cognitive frailty (physical frailty plus pre-MCI subjective cognitive decline). Here the prevalence of a potentially reversible cognitive frailty model was estimated. It was also evaluated if introducing a diagnosis of MCI in older subjects with physical frailty could have an additive role on the risk of dementia, disability, and all-cause mortality in comparison with frailty state or MCI condition alone, with analyses separately performed for inflammatory state.

Autore Pugliese

Tutti gli autori

  • DANIELE A.;SABBA' C.;ABBRESCIA D.I.;PANZA F.;LOGROSCINO G.;LOZUPONE M.;GIANNINI M.;SARDONE R.;SOLFRIZZI V.

Titolo volume/Rivista

Non Disponibile

Anno di pubblicazione

2017

ISSN

1064-7481

ISBN

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Numero di citazioni Wos

Nessuna citazione

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Numero di citazioni Scopus

8

Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

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