Abstract

The spatial distribution of mast cells inside the tumor stroma has been little investigated. In this study, we have evaluated tumor mast cells distribution through the analysis of the morphological features of the spatial patterns generated by these cells, including size, shape, and architecture of the cell pattern. We have compared diffuse large B cells lymphoma (DLBCL) and systemic mastocytosis in two different anatomical localizations (lymph nodes for DLBCL and, respectively, bone marrow for mastocytosis). Results have indicated that, despite the high difference in size exhibited by the mast cells patterns in the two conditions, the spatial relationship between the mast cells forming the aggregates resulted similar, characterized by a significant tendency of the mast cells to self-organize in clusters.

Autore Pugliese

• Rizzi Anna , Ribatti Domenico , Maiorano Eugenio , Specchia Giorgina

Tutti gli autori

• RIZZI A.;MARINACCIO C.;RIBATTI D.;MAIORANO E.;SPECCHIA G.;RUGGIERI S.

Titolo volume/Rivista

Non Disponibile

Anno di pubblicazione

2015

ISSN

0014-4827

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

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Numero di citazioni Scopus

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Ultimo Aggiornamento Citazioni

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Settori ERC

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Codici ASJC

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