23-valent pneumococcal vaccine failure in a patient who developed pneumonia: a case report

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Abstract

We report a clinical failure of a pneumococcal vaccine in a patient who developed pneumococcal pneumonia. In 2008, an 85-year-old Italian woman was admitted to the Respiratory Disease Unit of a hospital in Southern Italy. The 23-valent pneumococcal vaccine had been administered to the patient 50 days earlier. The chest x-ray disclosed a right basal bronchopneumonic focus. Streptococcus Pneumoniae serotype 19A, a strain included in the 23-valent pneumococcal vaccine, was isolated from the sputum. There is a need for more efficacious conjugated vaccines covering the majority of the pneumococcal serotypes that cause serious illness in older children and adults worldwide.

Autore Pugliese

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  • GRIMALDI A.;MARTINELLI D.;PRATO R.;TAFURI S.

Titolo volume/Rivista

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Anno di pubblicazione

2011

ISSN

1121-7138

ISBN

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Numero di citazioni Wos

1

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Numero di citazioni Scopus

1

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Settori ERC

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Codici ASJC

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