Pneumococcal pneumonia prevention among adults: is the herd effect of pneumococcal conjugate vaccination in children as good a way as the active immunization of the elderly?

Abstract

The indirect protection of adults as a result of pneumococcal conjugate vaccination of infants has been discussed from different epidemiological points of view. In some countries, including Italy, even after pediatric vaccination, vaccine serotypes are still responsible for most pneumonia and invasive diseases in the elderly. Although the Community-Acquired Pneumonia Immunization Trial in Adults (CAPITA) produced encouraging results, it has not showed the efficacy of the 13-valent conjugate vaccine in preventing pneumococcal community-acquired pneumonia regardless of the number of episodes and serotype. Addressing these points by monitoring the direct impact of adult vaccination in real life distinguished from the effects of herd immunity will assist public health decision-making on the most effective adult pneumococcal vaccination strategies.


Autore Pugliese

Tutti gli autori

  • Prato R. , Fortunato F. , Martinelli D.

Titolo volume/Rivista

CURRENT MEDICAL RESEARCH AND OPINION


Anno di pubblicazione

2016

ISSN

0300-7995

ISBN

Non Disponibile


Numero di citazioni Wos

6

Ultimo Aggiornamento Citazioni

Non Disponibile


Numero di citazioni Scopus

6

Ultimo Aggiornamento Citazioni

Non Disponibile


Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile