Abstract

The Rieske iron-sulfur protein, one of the catalytic subunits of the cytochrome complex, is involved in electron transfer at the level of the inner membrane of yeast mitochondria. The Rieske iron-sulfur protein is encoded by nuclear DNA and, after being synthesized in the cytosol, is imported into mitochondria with the help of a cleavable N-terminal presequence. The imported protein, besides incorporating the 2Fe-2S cluster, also interacts with other catalytic and non-catalytic subunits of the cytochrome complex, thereby assembling into the mature and functional respiratory complex. In this paper, we summarize the most recent findings on the import and assembly of the Rieske iron-sulfur protein into Saccharomyces cerevisiae mitochondria, also discussing a possible role of this protein both in the dimerization of the cytochrome complex and in the interaction of this homodimer with other complexes of the mitochondrial respiratory chain.

Autore Pugliese

• Zara Vincenzo

Tutti gli autori

• Conte L. , Zara V.

Titolo volume/Rivista

BIOINORGANIC CHEMISTRY AND APPLICATIONS

Anno di pubblicazione

2011

ISSN

1565-3633

ISBN

Non Disponibile

Numero di citazioni Wos

10

Ultimo Aggiornamento Citazioni

28/04/2018

Numero di citazioni Scopus

13

Ultimo Aggiornamento Citazioni

28/04/2018

Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile