Rapid down-regulation of hepatic lipid metabolism by phenolic fraction from extra virgin olive oil

Abstract

Regular consumption of extra virgin olive oil (EVOO) is associated with a low incidence of atherosclerotic diseases. The phenolic component contributes to the hypolipidemic action of EVOO, although the biochemical mechanisms leading this beneficial outcome are not fully understood. Since liver plays a pivotal role in the whole body lipid homeostasis, we investigated the short-term effects of EVOO extract, with a high phenol content (HPE), on lipid synthesis in primary rat hepatocytes. Refined olive oil extract, with a low phenol content, was used throughout this study as a control.


Autore Pugliese

Tutti gli autori

  • Priore P. , Caruso D. , Siculella L. , Gnoni G.V.

Titolo volume/Rivista

EUROPEAN JOURNAL OF NUTRITION


Anno di pubblicazione

2015

ISSN

1436-6207

ISBN

Non Disponibile


Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

Non Disponibile


Numero di citazioni Scopus

6

Ultimo Aggiornamento Citazioni

28/04/2018


Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile