Abstract

Introduction. Sepsis is a major cause of significant morbidity and mortality in neutropenic patients. Blood culture remains the gold standard in the microbiological diagnosis of bacterial or fungal bloodstream infections, but it has clear limits of rapid- ity and sensitivity. The objective of the study was to compare the real-time polymerase chain reaction (RT-PCR) with auto- mated blood cultures (BC) method in detection in whole blood of pathogens in febrile neutropenic patients with hematological malignancies. Methods. A total of 166 consecutive febrile neutropenic patients were enrolled. Blood samples for cultures and SeptiFast testing were obtained at the onset of fever, before the implementation of empirical antibiotic therapy.

Autore Pugliese

• Guido Marcello , De Donno Maria Antonella

Tutti gli autori

• Guido M. , Quattrocchi M. , Zizza A. , Pasanisi G. , Pavone V. , Lobreglio G. , De Donno A.

Titolo volume/Rivista

JOURNAL OF PREVENTIVE MEDICINE AND HYGIENE

Anno di pubblicazione

2012

ISSN

1121-2233

ISBN

Non Disponibile

Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

Non Disponibile

Numero di citazioni Scopus

15

Ultimo Aggiornamento Citazioni

28/04/2018

Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile