Human metapneumovirus and human bocavirus associated with respiratory infection in Apulian population.
Abstract
We have studied the occurrence of hBoV, hMPV and InfA-B in an Apulian population with respiratory tract infections. During influenza season 2008-2009, 116 oropharingeal swabs were collected from patients affected by Influenza-Like Illness (ILI). The PCR products of hMPV M and HBoV NP-1 genes were sequenced. 78 out of 116 samples were positive for at least one respiratory virus; hBoV was detected in 53, hMPV in 22 and InfA-B in 41 out of 116 swabs. A high rate of hBoV infection in adult (18.9%) and elderly (26.4%) subjects was found. The co-infection rate was higher for hMPV (18/22 cases, 81.8%) compared to hBoV (26/53 cases, 49.1%), and InfA-B (25/41 cases, 61.0%). Co-infections were common in children. hBoV positive samples shared a high level of genetic similarity with the hBoV1 genotype, and hMPV positive samples clustered with A2 subgroup. Our results suggest that hBoV and hMPV play a role in ILI.
Autore Pugliese
Tutti gli autori
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Guido M. , Quattrocchi M. , Campa A. , Zizza A. , Grima P. , Romano A. , De Donno A.
Titolo volume/Rivista
VIROLOGY
Anno di pubblicazione
2011
ISSN
0042-6822
ISBN
Non Disponibile
Numero di citazioni Wos
11
Ultimo Aggiornamento Citazioni
28/04/2018
Numero di citazioni Scopus
14
Ultimo Aggiornamento Citazioni
28/04/2018
Settori ERC
Non Disponibile
Codici ASJC
Non Disponibile
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