Abstract

Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma. Viral persistence and pathogenesis are due to the ability of HCV to deregulate specific host processes, mainly lipid metabolism and innate immunity. In particular, HCV exploits the lipoprotein machineries for almost all steps of its life cycle. The aim of this review is to summarize current knowledge concerning the interplay between HCV and lipoprotein metabolism. We discuss the role played by members of lipoproteins in HCV entry, replication and virion production.

Autore Pugliese

• Fimia Gian Maria

Tutti gli autori

• Grassi G. , Di Caprio G. , Fimia G.M. , Ippolito G. , Tripodi M. , Alonzi T.

Titolo volume/Rivista

WORLD JOURNAL OF GASTROENTEROLOGY

Anno di pubblicazione

2016

ISSN

1007-9327

ISBN

Non Disponibile

Numero di citazioni Wos

6

Ultimo Aggiornamento Citazioni

25/04/2018

Numero di citazioni Scopus

8

Ultimo Aggiornamento Citazioni

26/04/2018

Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile