Efficacy of silver treated catheters for haemodialysis in preventing bacterial adhesion

Abstract

The growing resistance of many strains of bacteria to antibiotics and antiseptics is becoming a serious problem in medicine. Nano-silver is one of the most prominent products in medicine because it exhibits unusual physicochemical properties and a strong biological activity. In this work an innovative silver deposition technology was applied to temporary polyurethane catheters for haemodialysis. The working conditions of catheters were reproduced through laboratory equipment that ensured the flow of deionized water and simulated body fluid inside the lumina at corporeal temperature. The growth and the adhesion of Staphylococcus aureus on the surface of the device were studied through fluorescence microscopy. ICP-AES was adopted to calculate the amount of silver released from the substrate. The stability of the coating during the whole working life of the device was demonstrated through thermo-gravimetric analysis.


Tutti gli autori

  • Paladini F. , Pollini M. , Talà A. , Alifano P. , Sannino A.

Titolo volume/Rivista

JOURNAL OF MATERIALS SCIENCE. MATERIALS IN MEDICINE


Anno di pubblicazione

2012

ISSN

0957-4530

ISBN

Non Disponibile


Numero di citazioni Wos

28

Ultimo Aggiornamento Citazioni

28/04/2018


Numero di citazioni Scopus

30

Ultimo Aggiornamento Citazioni

28/04/2018


Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile