DETECTION AND MOLECULAR CHARACTERISATION OF HUMAN ROTAVIRUSES ISOLATED IN ITALY AND ALBANIA.
Abstract
Rotaviruses are one of the most important causes of gastroenteritis in children under 5 years old. Analysis of G and P rotavirus genotypes in circulation is crucial in evaluating the appropriacy of mass vaccination of children worldwide. Overall, 592 stool samples were collected in Tirana (Albania), the Salento peninsula (South Italy), and three different hospitals in Rome (Central Italy). Of the total samples, 31.3% were rotavirus positive in Albania, 78.3% in the Salento, and 40.3% in Rome. The samples collected in Tirana and Rome were G-P typed, whereas the samples collected in the Salento were only G typed. Overall, in Italy the most frequent combinations were G4 P[8] (54.5%), G1 P[8] (27.3%), and G2 P[4] (18.2%); in Albania they were G9 P[8] (72.1%), G4 P[8] (8.8%), G1 P[8] (5.9%), and G2 P[4] (2.9%). The prevalence in Albania of atypical combinations was 7.4% for G4 P[4] and 2.9% for G9 P[4]. Phylogenetic analysis was also performed to assess the genetic relatedness of the strains.
Autore Pugliese
Tutti gli autori
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A.R. Petrinca , T. Grassi , D. Donia , A. De Donno , A. Idolo , A. Cristaldi , C. Alessandri , A. Spanò , M. Divizia
Titolo volume/Rivista
JOURNAL OF MEDICAL VIROLOGY
Anno di pubblicazione
2010
ISSN
0146-6615
ISBN
Non Disponibile
Numero di citazioni Wos
8
Ultimo Aggiornamento Citazioni
28/04/2018
Numero di citazioni Scopus
9
Ultimo Aggiornamento Citazioni
22/04/2018
Settori ERC
Non Disponibile
Codici ASJC
Non Disponibile
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