Abstract

Objective: To show the prevention of adhesion formation by placing an absorbable adhesion barrier after intracapsular myomectomy. Design: Prospective blinded observational study. Setting: University-affiliated Hospitals. Patient(s): Patients R18 years old with single or multiple uterine fibroids removed by laparoscopic or abdominal intracapsular myomectomy. Intervention(s): A total of 694 women undergoing laparoscopic or abdominal myomectomy were randomized for placement of oxidized regenerated cellulose absorbable adhesion barrier to the uterine incision or for control subjects without barriers. The presence of adhesions was assessed in 546 patients who underwent subsequent surgery. MainOutcomeMeasure(s): Theprimaryandsecondaryoutcomesoftheanalysiswerethepresenceandseverityof adhesions for four groups: laparotomy with barrier, laparotomy without barrier, laparoscopy with barrier, and laparoscopy without barrier. Result(s): Therewasahigherrateofadhesionsinlaparotomywithoutbarrier(28.1%)comparedwithlaparoscopy with no barrier (22.6%), followed by laparotomy with barrier (22%) and laparoscopy with barrier (15.9%). Additionally, the type of adhesions were different, filmy and organized were predominant with an adhesion barrier, and cohesive adhesions were more common without an adhesion barrier. Conclusion(s): Oxidized regenerated cellulose reduces postsurgical adhesions. Cohesive adhesions reduction was noted in laparoscopy.

Autore Pugliese

• Guido Marcello

Tutti gli autori

• Tinelli A , Malvasi A , Guido M , Tsin DA , Hudelist G , Hurst B , Stark M , Mettler L.

Titolo volume/Rivista

FERTILITY AND STERILITY

Anno di pubblicazione

2011

ISSN

0015-0282

ISBN

Non Disponibile

Numero di citazioni Wos

30

Ultimo Aggiornamento Citazioni

23/04/2018

Numero di citazioni Scopus

42

Ultimo Aggiornamento Citazioni

23/04/2018

Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile