A molecularly imprinted polymer for the determination of neopterin

Abstract

A molecularly imprinted polymer (MIP) for the specific retention of neopterin has been developed. A set of 6 polymers was prepared by radical polymerization under different experimental condition using methacrylic acid as functional monomer and ethylene glycol dimethacrylate as crosslinker, with the aim to understand their influence on the efficiency of the MIP. The performance of each MIP was tested in batch experiments via their binding capacity. The MIP prepared in the presence of nickel ions in dimethylsulfoxide-acetonitrile mixture (P4) exhibited the highest binding capacity for neopterin (260 μmol per gram of polymer). A selectivity study with two other pteridines demonstrated the polymer P4 also to possess the best selectivity.


Autore Pugliese

Tutti gli autori

  • R. Del Sole , A. Scardino , M.R. Lazzoi , L. Mergola , S. Scorrano , G. Vasapollo

Titolo volume/Rivista

MICROCHIMICA ACTA


Anno di pubblicazione

2013

ISSN

1436-5073

ISBN

Non Disponibile


Numero di citazioni Wos

Nessuna citazione

Ultimo Aggiornamento Citazioni

Non Disponibile


Numero di citazioni Scopus

4

Ultimo Aggiornamento Citazioni

28/04/2018


Settori ERC

Non Disponibile

Codici ASJC

Non Disponibile