TARGETING NUCLEIC ACIDS IN MITOCHONDRIA

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Abstract

The present invention relates to a shuttle system with which nucleic acids of interest may be imported into a mitochondrion. This system is based on the use of a fusion protein between a mitochondrial targeting sequence and a protein binding a nucleic acid of interest. This shuttle system is for example useful in agronomics, in the field of gene therapy, and within the scope of research products aiming at characterizing the function of mitochondrial genes.

Classe Tecnologica

A - Human Necessities

Patent Office

United States Patent and Trademark Office

Numero Deposito

US2012110693

Anno Deposito

2009

Anno Concessione

2012

Inventori Pugliesi

Tutti gli inventori

  • Laurence Drouard
  • Antonio Placido
  • Francois Sieber

Titolari pugliesi

  • Non ci sono titolari pugliesi

Tutti i titolari

  • CNRS - CENTRE NATIONAL RECHERCHE SCIENTIFIQUE