PROCESS FOR THE PREPARATION OF FOSINOPRIL AND INTERMEDIATES THEREOF

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Abstract

The present invention relates to a process for the preparation of intermediates useful in the synthesis of [1[S(R)],2±,4²]-4-cyclohexyl-1-[[[2-methyl-1-oxypropoxy) propoxy](4-phenylbutyl phosphinyl]acetyl]-L-proline, and the synthesis thereof, in particular as sodium salt (fosinopril sodium).

Classe Tecnologica

C - Chemistry and Metallurgy

Patent Office

United States Patent and Trademark Office

Numero Deposito

US2012142939

Anno Deposito

2010

Anno Concessione

2012

Inventori Pugliesi

  • Attolino Emanuele

Tutti gli inventori

  • Pietro Allegrini
  • Emanuele Attolino
  • Alessandro De Marco
  • Fausto Gorassini
  • Mario Michieletti

Titolari pugliesi

  • Non ci sono titolari pugliesi

Tutti i titolari

  • Dipharma Francis S.r.l.