Optical Apparatus and Method for the Inspection of Nucleic Acid Probes by Polarized Radiation

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Abstract

An optical apparatus for the inspection of nucleic acid probes includes: a holder (22) for housing a chip (1) for analysis of nucleic acids, containing nucleic acid probes (12, 12'); a light (24), for supplying an excitation radiation (WE) to the holder (22); and an optical sensor (25) for detecting images (IMG) of the nucleic acid probes (12, 12'), when a chip (1) is housed in the holder (22). The light source (24) is configured for polarizing the excitation radiation (WE) according to a excitation polarization direction (DE). Furthermore, the apparatus is provided with a sensing polarizing filter (27), which is arranged so as to intercept a reflected portion (WR) of the excitation radiation (WE), directed towards the optical sensor (25). The sensing polarizing filter (27) has a direction of the sensing polarization (DS) transverse to the excitation polarization direction (DE).

Classe Tecnologica

G - Physics

Patent Office

United States Patent and Trademark Office

Numero Deposito

US2009303479

Anno Deposito

2006

Anno Concessione

2009

Inventori Pugliesi

Tutti gli inventori

  • Ferrara Francesco
  • Calabi Franco
  • Rinaldi Rosaria

Titolari pugliesi

  • Non ci sono titolari pugliesi

Tutti i titolari

  • STMicroeletronics S.r.l.