Nucleic acid analysis chip integrating a waveguide and optical apparatus for the inspection of nucleic acid probes

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Abstract

A chip for nucleic acid analysis includes a body (2, 9) , in which a detection chamber (7) is formed for accommodating nucleic acid probes (12, 12') . A waveguide (8) is integrated in the body (2, 9) is and is arranged at the bottom of the detection chamber (7) so that an evanescent wave (EW) , produced at an interface (8a) of the waveguide (8) when a light radiation is conveyed within the waveguide (8), is irradiated towards the inside of the detection chamber (7) . An apparatus for inspection of nucleic acid probes includes: a holder (22) , on which a chip (1) for nucleic acid analysis is loaded, the chip containing nucleic acid probes (12, 12'); a light source (24) for supplying an excitation radiation to the nucleic acid probes (12, 12'); and an optical sensor (25) arranged so as to receive radiation coming from the nucleic acid probes (12, 12') .

Classe Tecnologica

C - Chemistry and Metallurgy

Patent Office

United States Patent and Trademark Office

Numero Deposito

US8062595

Anno Deposito

2006

Anno Concessione

2011

Inventori Pugliesi

Tutti gli inventori

  • Ferrara Francesco
  • Pompa Pier Paolo
  • Rinaldi Rosaria

Titolari pugliesi

  • Non ci sono titolari pugliesi

Tutti i titolari

  • STMicroeletronics S.r.l.